Article
Characterization of photodynamic therapy responses elicited in A431 cells containing intracellular organelle-localized photofrin.
Journal of cellular biochemistry - 1 Nov 2010
Hsieh Ya-Ju, Yu Jau-Song, Lyu Ping-Chiang
Abstract excerpt
Photodynamic therapy (PDT), a photochemotherapeutic regimen used to treat several diseases, including cancer, exerts its effects mainly through induction of cell death. Using human epidermoid carcinoma A431 cells as a model, we previously showed that distinct cell death types could be triggered by protocols that selectively delivered Photofrin (a clinically approved photosensitizer) to different subcellular sites...
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