Article
Cloning, expression, and polymorphisms of natural killer cell receptor NCR1 in pigs.
Animal biotechnology - 1 Jul 2010
Jozaki Kosuke, Shinkai Hiroki, Morozumi Takeya, Tanaka-Matsuda Maiko, Eguchi-Ogawa Tomoko, Wada Yasuhiko, Uenishi Hirohide
Abstract excerpt
NCR1 (NKp46) is expressed on the surfaces of natural killer cells and recognizes hemagglutinin on the influenza virus. We cloned the NCR1 gene in pigs and found that porcine NCR1 was minimally expressed in the thymus, suggesting that NCR1 could be a useful marker of natural killer cells in pigs. We observed three nonsynonymous single nucleotide polymorphisms and one deletion of three nucleotides in the coding...
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