Analysis of polymorphism in porcine MHC class I genes: alterations in signals recognized by human cytotoxic lymphocytes.

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Article

Analysis of polymorphism in porcine MHC class I genes: alterations in signals recognized by human cytotoxic lymphocytes.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 1997

Sullivan J A, Oettinger H F, Sachs D H, Edge A S

Abstract excerpt

Elucidation of the mechanism of the immune response against transplanted porcine tissue is critical for the success of xenografting in humans. Both human T cells and NK cells recognize MHC Ags, and human receptors may bind to MHC Ags across species barriers. Molecular characterization of porcine...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Binding Sites
CD8 Antigens
Cytotoxicity, Immunologic
DNA, Complementary
Genes, MHC Class I
Histocompatibility Antigens
Humans
Killer Cells, Natural

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Polymorphism, Genetic

Sequence Alignment

Sequence Homology, Nucleic Acid

Species Specificity

Swine

Source

Open in PubMed

Identifiers

PMID: 9278321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9278321-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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