Article
Genetic polymorphisms in Matrix Metalloproteinases -1 and -7 and susceptibility to gastric cancer: an association study and meta-analysis.
Iranian journal of allergy, asthma, and immunology - 9 Jul 2013
Fang Wen-Liang, Liang Wei-Bo, Gao Lin-Bo, Zhou Bin, Xiao Feng-Li, Zhang Lin
Abstract excerpt
Matrix Metalloproteinases (MMPs) play an important role in gastric cancer (GC). Accumulated evidence suggests that functional MMP-1 and MMP-7 gene polymorphisms are associated with several tumors. The aim of this study was to investigate two single nucleotide polymorphisms, MMP-1 -1607 1G/2G and MMP-7 -181 A/G, and their potential relationship with GC. We examined 246 GC patients and 252 age-and sex-matched...
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