Article
Association of MMP7-181A/G and MMP13-77A/G polymorphisms with colorectal cancer in a Mexican population.
Genetics and molecular research : GMR - 14 Feb 2014
Moreno-Ortiz J M, Gutiérrez-Angulo M, Partida-Pérez M, Peregrina-Sandoval J, Ramírez-Ramírez R, Muñiz-Mendoza R, Suárez-Villanueva S, Centeno-Flores M, Maciel-Gutiérrez V, Cabrales-Vazquez J E, Ayala-Madrigal M L
Abstract excerpt
Colorectal cancer (CRC) is characterized by enhanced expression and activity of several metalloproteinases (MMPs), including MMP13 and MMP7, which play an important role in tumor invasion and metastasis. The objective of this study was to analyze the association of functional MMP7-181A/G and MMP13-77A/G promoter polymorphisms with susceptibility to CRC in a Mexican population. Genomic DNA samples were obtained...
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