Article
Core glycan in the yeast multicopper ferroxidase, Fet3p: a case study of N-linked glycosylation, protein maturation, and stability.
Protein science : a publication of the Protein Society - 1 Sept 2010
Ziegler Lynn, Terzulli Alaina, Sedlak Erik, Kosman Daniel J
Abstract excerpt
Glycosylation is essential to the maintenance of protein quality in the vesicular protein trafficking pathway in eukaryotic cells. Using the yeast multicopper oxidase, Fet3p, the hypothesis is tested that core glycosylation suppresses Fet3p nascent chain aggregation during synthesis into the endo...
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