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Article

Quantification and application of the placental epigenetic signature of the <i>RASSF1A</i> gene in maternal plasma

27 May 2010

Abstract excerpt

OBJECTIVES: The aims of the detection of hypermethylated RASSF1A gene in maternal plasma from all three trimesters of pregnancy were to show its feature of cell-free fetal DNA and to make up deficients of genetic markers. This study also aimed at investigating of its application value in pre-eclampsia compared with third trimester. METHODS: Eighty pregnant women (7-41 gestational weeks) including normal pregnant...

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Share to Epigenetics and DNA Methylation
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Share to Prenatal Screening and Diagnostics

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PMID: 20661892
DOI: 10.1002/pd.2546

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