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Article

Quantitative aberrations of hypermethylated <i>RASSF1A</i> gene sequences in maternal plasma in pre‐eclampsia

12 Nov 2007

Abstract excerpt

OBJECTIVE: To study if quantitative aberrations in circulating placental-derived hypermethylated RASSF1A DNA in maternal plasma are associated with pre-eclamptic pregnancies. METHOD: Maternal plasma and placental tissues from third-trimester pre-eclamptic women and gestational-age matched normotensive controls were studied. Real-time PCR was performed to quantify RASSF1A concentrations before and after...

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Share to Epigenetics and DNA Methylation
Share to Pregnancy and preeclampsia studies
Share to Prenatal Screening and Diagnostics

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PMID: 17994635
DOI: 10.1002/pd.1897

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