Article
Schizophrenia gene networks and pathways and their applications for novel candidate gene selection.
PloS one - 29 Jun 2010
Sun Jingchun, Jia Peilin, Fanous Ayman H, van den Oord Edwin, Chen Xiangning, Riley Brien P, Amdur Richard L, Kendler Kenneth S, Zhao Zhongming
Abstract excerpt
BACKGROUND: Schizophrenia (SZ) is a heritable, complex mental disorder. We have seen limited success in finding causal genes for schizophrenia from numerous conventional studies. Protein interaction network and pathway-based analysis may provide us an alternative and effective approach to investigating the molecular mechanisms of schizophrenia. METHODOLOGY/PRINCIPAL FINDINGS: We selected a list of schizophrenia...
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