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A hypothesis-driven pathway analysis reveals myelin-related pathways that contribute to the risk of schizophrenia and bipolar disorder.

Progress in neuro-psychopharmacology & biological psychiatry - 3 Jun 2014

Yu Hao, Bi Wenjian, Liu Chenxing, Zhao Yanlong, Zhang Dai, Yue Weihua

Abstract excerpt

Schizophrenia (SZ) and bipolar disorder (BD) are both severe neuropsychiatric disorders with a strong and potential overlapping genetic background. Multiple lines of evidence, including genetic studies, gene expression studies and neuroimaging studies, have suggested that both disorders are closely related to myelin and oligodendrocyte dysfunctions. In the current study, we hypothesized that the holistic effect...

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PMID: 24447946
DOI: 10.1016/j.pnpbp.2014.01.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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