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Article

HFE gene variants modify the association between maternal lead burden and infant birthweight: a prospective birth cohort study in Mexico City, Mexico.

Environmental health : a global access science source - 26 Jul 2010

Cantonwine David, Hu Howard, Téllez-Rojo Martha Maria, Sánchez Brisa N, Lamadrid-Figueroa Héctor, Ettinger Adrienne S, Mercado-García Adriana, Hernández-Avila Mauricio, Wright Robert O

Abstract excerpt

BACKGROUND: Neonatal growth is a complex process involving genetic and environmental factors. Polymorphisms in the hemochromatosis (HFE) iron regulatory genes have been shown to modify transport and toxicity of lead which is known to affect birth weight. METHODS: We investigated the role of HFE C282Y, HFE H63 D, and transferrin (TF) P570 S gene variants in modifying the association of lead and infant birthweight...

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Identifiers

PMID: 20659343
DOI: 10.1186/1476-069X-9-43
PMCID: PMC2916893

Genes

HFE

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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