Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maternal iron metabolism gene variants modify umbilical cord blood lead levels by gene-environment interaction: a birth cohort study.

Environmental health : a global access science source - 6 Oct 2014

Karwowski Mateusz P, Just Allan C, Bellinger David C, Jim Rebecca, Hatley Earl L, Ettinger Adrienne S, Hu Howard, Wright Robert O

Abstract excerpt

BACKGROUND: Given the relationship between iron metabolism and lead toxicokinetics, we hypothesized that polymorphisms in iron metabolism genes might modify maternal-fetal lead transfer. The objective of this study was to determine whether maternal and/or infant transferrin (TF) and hemochromatosis (HFE) gene missense variants modify the association between maternal blood lead (MBL) and umbilical cord blood lead...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fetal Blood
Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemochromatosis Protein

Share to Histocompatibility Antigens Class I

Share to Linear Models

Share to Multiplex Polymerase Chain Reaction

Share to Transferrin

Source

Open in PubMed Open full text

Identifiers

PMID: 25287020
DOI: 10.1186/1476-069X-13-77
PMCID: PMC4271345

Genes

HFE
TF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Maternal iron metabolism gene variants modify umbilical cord blood lead levels by gene-environment interaction: a birth cohort study.PMID 25287020Read ↗

Variants in iron metabolism genes predict higher blood lead levels in young children.Semantic proximity Read ↗

HFE gene variants modify the association between maternal lead burden and infant birthweight: a prospective birth cohort study in Mexico City, Mexico.Semantic proximity Read ↗

Hereditary hemochromatosis gene (HFE) variants are associated with birth weight and childhood leukemia risk.Semantic proximity Read ↗

Maternal hemochromatosis gene H63D single-nucleotide polymorphism and lead levels of placental tissue, maternal and umbilical cord blood.Semantic proximity Read ↗

Evidence of genetic effects on blood lead concentration.Semantic proximity Read ↗

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.Semantic proximity Read ↗

Blood lead levels, iron metabolism gene polymorphisms and homocysteine: a gene-environment interaction study.Semantic proximity Read ↗

Does maternal VDR FokI single nucleotide polymorphism have an effect on lead levels of placenta, maternal and cord bloods?Semantic proximity Read ↗

Associations of iron metabolism genes with blood manganese levels: a population-based study with validation data from animal models.Semantic proximity Read ↗

Classification and genetic features of neonatal haemochromatosis: a study of 27 affected pedigrees and molecular analysis of genes implicated in iron metabolismSemantic proximity Read ↗

Vitamin D receptor haplotypes affect lead levels during pregnancy.Semantic proximity Read ↗

Effect modification by transferrin C2 polymorphism on lead exposure, hemoglobin levels, and IQ.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.