Article
Generation of ramoplanin-resistant Staphylococcus aureus.
FEMS microbiology letters - 1 Sept 2010
Schmidt John W, Greenough Adrienne, Burns Michelle, Luteran Andrea E, McCafferty Dewey G
Abstract excerpt
Ramoplanin is a lipoglycodepsipeptide antimicrobial active against clinically important Gram-positive bacteria including methicillin-resistant Staphylococcus aureus. To proactively examine ramoplanin resistance, we subjected S. aureus NCTC 8325-4 to serial passage in the presence of increasing concentrations of ramoplanin, generating the markedly resistant strain RRSA16. Susceptibility testing of RRSA16 revealed...
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