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Article

CHEK2 I157T and colorectal cancer in Bulgaria.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000

Konstantinova D, Kadiyska T, Sokolova V, Kaneva R, Mirchev M, Savov A, Aleksandrova A, Nedin D, Kostadinov E, Damyanov D, Kremensky I, Mitev V

Abstract excerpt

PURPOSE: Germline variants of the CHEK2 gene have been shown to act as low-penetrance cancer susceptibility alleles for a wide range of human malignancies. CHEK2 I157T has particularly been linked to colorectal cancer (CRC) risk. We aimed at establishing the population frequency and contribution of this variant to colorectal carcinogenesis in Bulgaria. METHODS: We have genotyped 802 population controls and 343...

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Source

Identifiers

PMID: 20658728

Genes

CHEK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

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CHEK2 I157T and colorectal cancer in Bulgaria.PMID 20658728Read ↗

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