Article
Female X-chromosome mosaicism for gp91phox expression diversifies leukocyte responses during endotoxemia.
Critical care medicine - 1 Oct 2010
Chandra Rachna, Federici Stephanie, Haskó György, Deitch Edwin A, Spolarics Zoltán
Abstract excerpt
OBJECTIVE: To test the hypothesis, using an animal model, whether female X-chromosome mosaicism for inflammatory gene expression could contribute to the gender dimorphic response during the host response. X-chromosome-linked genetic polymorphisms present a unique biological condition because fema...
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