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Article

The MAP kinase Pmk1 and protein kinase A are required for rotenone resistance in the fission yeast, Schizosaccharomyces pombe.

Biochemical and biophysical research communications - 20 Aug 2010

Wang Yiwei, Gulis Galina, Buckner Scott, Johnson P Connor, Sullivan Daniel, Busenlehner Laura, Marcus Stevan

Abstract excerpt

Rotenone is a widely used pesticide that induces Parkinson's disease-like symptoms in rats and death of dopaminergic neurons in culture. Although rotenone is a potent inhibitor of complex I of the mitochondrial electron transport chain, it can induce death of dopaminergic neurons independently of...

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Source

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Identifiers

PMID: 20655879
DOI: 10.1016/j.bbrc.2010.07.014
PMCID: PMC2926249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20655879-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The MAP kinase Pmk1 and protein kinase A are required for rotenone resistance in the fission yeast, Schizosaccharomyces pombe.PMID 20655879Read ↗

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