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Article

Origin and diversification of steroids: co-evolution of enzymes and nuclear receptors.

Molecular and cellular endocrinology - 1 Mar 2011

Baker Michael E

Abstract excerpt

Recent sequencing of amphioxus and sea urchin genomes has provided important data for understanding the origins of enzymes that synthesize adrenal and sex steroids and the receptors that mediate physiological response to these vertebrate steroids. Phylogenetic analyses reveal that CYP11A and CYP19, which are involved in the synthesis of adrenal and sex steroids, first appear in the common ancestor of amphioxus...

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Source

Identifiers

PMID: 20654689
DOI: 10.1016/j.mce.2010.07.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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