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Article

Conceptualizing the Vertebrate Sterolbiome

8 Jun 2020

Abstract excerpt

Vertebrates synthesize a diverse set of steroids and bile acids that undergo bacterial biotransformations. The endocrine literature has principally focused on the biochemistry and molecular biology of host synthesis and tissue-specific metabolism of steroids. Host-associated microbiota possess a coevolved set of steroid and bile acid modifying enzymes that match the majority of host peripheral biotransformations...

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PMID: 32503912
DOI: 10.1128/aem.00641-20

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