Characterization of a novel open reading frame, urf a, in the mitochondrial genome of fission yeast: correlation of urf a mutations with a mitochondrial mutator phenotype and a possible role of frameshifting in urf a expression.

doi:10.1007/BF00326289

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Characterization of a novel open reading frame, urf a, in the mitochondrial genome of fission yeast: correlation of urf a mutations with a mitochondrial mutator phenotype and a possible role of frameshifting in urf a expression.

Current genetics - 1 Feb 1991

Zimmer M, Krabusch M, Wolf K

Abstract excerpt

Between the genes for tRNA(gin) and tRNA(ile) an open reading frame of 227 amino acids has been identified which is unique among known mitochondrial genomes and which has been termed urf a (Lang et al. 1983; Kornrumpf et al. 1984). It uses the "mitochondrial" genetic code, i.e., it contains a TGA codon, whereas all other protein-encoding genes, and all but one intronic open reading frame, use the "standard"...

Topics

Amino Acid Sequence
Base Sequence
Codon
DNA, Fungal
DNA, Mitochondrial
Extrachromosomal Inheritance
Frameshift Mutation
Fungal Proteins
Gene Expression Regulation, Fungal
Glycerol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mitochondrial Proteins

Molecular Sequence Data

Mutation

Open Reading Frames

Phenotype

Schizosaccharomyces

Schizosaccharomyces pombe Proteins

Source

Open in PubMed

Identifiers

PMID: 2065367
DOI: 10.1007/BF00326289

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2065367-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Characterization of a novel open reading frame, urf a, in the mitochondrial genome of fission yeast: correlation of urf a mutations with a mitochondrial mutator phenotype and a possible role of frameshifting in urf a expression.PMID 2065367Read ↗

Relocation of urf a from the mitochondrion to the nucleus cures the mitochondrial mutator phenotype in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Isolation and characterisation of nuclear mutants with enhanced mitochondrial mutability in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Mutations in yeast mt tRNAs: specific and general suppression by nuclear encoded tRNA interactors.Semantic proximity Read ↗

Structural and functional role of bases 32 and 33 in the anticodon loop of yeast mitochondrial tRNAIle.Semantic proximity Read ↗

Alpha subunit of mitochondrial F1-ATPase from the fission yeast. Deduced sequence of the wild type and identification of a mutation that alters apparent negative cooperativity.Semantic proximity Read ↗

Beta subunit of mitochondrial F1-ATPase from the fission yeast. Deduced sequence of the wild type protein and identification of a mutation that increases nucleotide binding.Semantic proximity Read ↗

Mutational studies of the major tRNA region of the S. cerevisiae mitochondrial genome.Semantic proximity Read ↗

A novel type of + 1 frameshift suppressor: a base substitution in the anticodon stem of a yeast mitochondrial serine-tRNA causes frameshift suppression.Semantic proximity Read ↗

An yeast nuclear mutation conferring temperature-sensitivity to the mitochondrial tryptophanyl-tRNA synthetase.Semantic proximity Read ↗

Translational readthrough of a termination codon in the yeast mitochondrial mRNA VAR1 as a result of mutation in the release factor mRF1.Semantic proximity Read ↗

Regulation by nuclear genes of the mitochondrial synthesis of subunits 6 and 8 of the ATP synthase of Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.