Article
A novel type of + 1 frameshift suppressor: a base substitution in the anticodon stem of a yeast mitochondrial serine-tRNA causes frameshift suppression.
The EMBO journal - 1 Feb 1990
Hüttenhofer A, Weiss-Brummer B, Dirheimer G, Martin R P
Abstract excerpt
We have identified a spontaneous mitochondrial mutation, mfs-1 (mitochondrial frameshift suppressor-1), which suppresses a + 1 frameshift mutation localized in the yeast mitochondrial oxi1 gene. The suppressor strain exhibits a single base change (C to U) at position 42 of the mitochondrial serin...
Topics
- Anticodon
- Base Sequence
- Genes, Fungal
- Mitochondria
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- RNA
- RNA, Mitochondrial
- RNA, Transfer
- RNA, Transfer, Amino Acid-Specific
- RNA, Transfer, Ser
- Saccharomyces cerevisiae
- Suppression, Genetic
- Transcription, Genetic