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Article

Influence of TNF-α-308 G/A gene polymorphism on temporomandibular disorder.

American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics - 1 May 2016

Furquim Bruno D'Aurea, Flamengui Lívia Maria Sales Pinto, Repeke Carlos Eduardo Palanch, Cavalla Franco, Garlet Gustavo Pompermaier, Conti Paulo César Rodrigues

Abstract excerpt

INTRODUCTION: Tumor necrosis factor alpha (TNF-α) levels are significantly upregulated in the synovial fluid of patients with temporomandibular joint disorder (TMD). The TNF-α influences pain generation and maintenance. Therefore, the aim of this study was to investigate the influence of single nucleotide polymorphism TNFA-308 (rs1800629) on TMD risk and on the pressure pain threshold. METHODS: The genotypic and...

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PMID: 27131251
DOI: 10.1016/j.ajodo.2015.10.026

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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