Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cells

19 Jul 2010

Abstract excerpt

Our understanding of how mesodermal tissue is formed has been limited by the absence of specific and reliable markers of early mesoderm commitment. We report that mesoderm commitment from human embryonic stem cells (hESCs) is initiated by epithelial-to-mesenchymal transition (EMT) as shown by gene expression profiling and by reciprocal changes in expression of the cell surface proteins, EpCAM/CD326 and NCAM/CD56....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital heart defects research
Share to Pluripotent Stem Cells Research
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20643952
DOI: 10.1073/pnas.1002077107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mapping the first stages of mesoderm commitment during differentiation of human embryonic stem cellsPMID 20643952Read ↗

Identification of the niche and phenotype of the first human hematopoietic stem cells.Semantic proximity Read ↗

CD32 allows capturing blood cells emergence in slow motion during human embryonic developmentSemantic proximity Read ↗

Mesoderm-Derived Stem Cells: The Link Between the Transcriptome and Their Differentiation PotentialSemantic proximity Read ↗

Characterization of migratory primordial germ cells in the aorta-gonad-mesonephros of a 4.5-week-old human embryo: a toolbox to evaluate in vitro early gametogenesisSemantic proximity Read ↗

Detailed characterization of the human aorta‐gonad‐mesonephros region reveals morphological polarity resembling a hematopoietic stromal layerSemantic proximity Read ↗

SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular developmentSemantic proximity Read ↗

NANOG and CDX2 Pattern Distinct Subtypes of Human Mesoderm during Exit from PluripotencySemantic proximity Read ↗

CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem CellsSemantic proximity Read ↗

Human embryonic stem cell-derived mesoderm-like epithelium transitions to mesenchymal progenitor cells.Semantic proximity Read ↗

Multilineage differentiation potential of cells isolated from the human amniotic membrane.Semantic proximity Read ↗

Identification and Purification of Mesodermal Progenitor Cells From Human Adult Bone MarrowSemantic proximity Read ↗

Transcriptomic and phenotypic analysis of murine embryonic stem cell derived BMP2+ lineage cells: an insight into mesodermal patterning.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.