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Article

SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development

4 May 2014

Abstract excerpt

The study of human cardiogenesis would benefit from a detailed cell lineage fate map akin to that established for the haematopoietic lineages. Here we sought to define cell lineage relationships based on the expression of NKX2-5 and the cell surface markers VCAM1, SIRPA and CD34 during human cardiovascular development. Expression of NKX2-5(GFP) was used to identify cardiac progenitors and cardiomyocytes generated...

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PMID: 24968096
DOI: 10.1016/j.scr.2014.04.016

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