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Article

Human embryonic stem cell-derived mesoderm-like epithelium transitions to mesenchymal progenitor cells.

Tissue engineering. Part A - 1 Aug 2009

Boyd Nolan L, Robbins Kelly R, Dhara Sujoy K, West Franklin D, Stice Steven L

Abstract excerpt

Human embryonic stem cells (hESC) have the potential to produce all of the cells in the body. They are able to self-renew indefinitely, potentially making them a source for large-scale production of therapeutic cell lines. Here, we developed a monolayer differentiation culture that induces hESC (WA09 and BG01) to form epithelial sheets with mesodermal gene expression patterns (BMP4, RUNX1, and GATA4). These...

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Source

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Identifiers

PMID: 19196144
DOI: 10.1089/ten.tea.2008.0351
PMCID: PMC2792108

Genes

BMP4
GATA4
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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