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The LysR-Type Transcriptional Regulator VirR Is Required for Expression of the Virulence GenevapAofRhodococcus equiATCC 33701

18 Aug 2004

Abstract excerpt

The virulence of the intracellular pathogen Rhodococcus equi in foals is dependent on the presence of an 81-kb virulence plasmid encoding the virulence protein VapA. Expression of this protein is induced by exposure to oxidative stress, high temperatures, and low pHs, which reflect the conditions encountered by R. equi when it enters the host environment. The aim of this study was to determine whether the...

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PMID: 15317761
DOI: 10.1128/jb.186.17.5576-5584.2004

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