Article
Prevalence of the mitochondrial A 1555G mutation in Moroccan patients with non-syndromic hearing loss.
International journal of pediatric otorhinolaryngology - 1 Sept 2010
Nahili Halima, Charif Majida, Boulouiz Redouane, Bounaceur Safaa, Benrahma Houda, Abidi Omar, Chafik Abdelaziz, Rouba Hassan, Kandil Mostafa, Barakat Abdelhamid
Abstract excerpt
UNLABELLED: Mutations in mitochondrial DNA (mtDNA), especially the A1555G transition in the 12S rRNA gene, are one of the causes of both aminoglycoside-induced and non-syndromic sensorineural hearing loss. OBJECTIVE: The aim of this study was to determine the prevalence of the A1555G mitochondrial mutation in Moroccan patients. METHODS: We performed molecular characterization by PCR-RFLP and direct sequencing of...
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