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Article

Screening of the mitochondrial A1555G mutation in patients with sensorineural hearing loss.

Brazilian journal of otorhinolaryngology - 1 Jan 2000

Maniglia Luciano Pereira, Moreira Bruna Carolina Lemos, da Silva Magali Aparecida Orate Menezes, Piatto Vânia Belintani, Maniglia José Victor

Abstract excerpt

UNLABELLED: The A1555G mitochondrial mutation is the main alteration associated with aminoglycoside-induced deafness. AIM: to investigate the prevalence of the A1555G mutation in patients sensorineural hearing loss patients with and without aminoglycosides antibiotic use. MATERIAL AND METHOD: a study of 27 cases with deafness as the sample, and 100 neonates with normal hearing as the control group. DNA was...

Topics

Adult
Aminoglycosides
Child
Child, Preschool
Cross-Sectional Studies
DNA, Mitochondrial
Female
Genetic Testing
Hearing Loss, Sensorineural
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Source

Open in PubMed Open full text

Identifiers

PMID: 19082356
DOI: 10.1016/S1808-8694(15)31384-7
PMCID: PMC9445927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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