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Article

[Familial susceptibility to aminoglycoside ototoxicity due to the A1555G mutation in the mitochondrial DNA].

Medicina clinica - 12 Jul 2003

Gallo-Terán Jaime, Morales-Angulo Carmelo, del Castillo Ignacio, Moreno-Pelayo Miguel Angel, Mazón Angel, Moreno Felipe

Abstract excerpt

BACKGROUND AND OBJECTIVE: The A1555G mutation in the mitochondrial genome causes sensorineural hearing loss and familial aminoglycoside ototoxicity. PATIENTS AND METHOD: Screening for the A1555G mutation was performed on 72 patients with nonsyndromic sensorineural hearing loss. RESULTS: The A1555G mutation was identified in 15 patients (20.8%). All of them presented maternal relatives with deafness. Individuals...

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Source

Identifiers

PMID: 12882732
DOI: 10.1016/s0025-7753(03)73909-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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