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Article

No association of the hypoxia-inducible factor-1α gene polymorphisms with survival in patients with colorectal cancer.

Medical oncology (Northwood, London, England) - 1 Dec 2011

Lee Soo Jung, Kim Jong Gwang, Sohn Sang Kyun, Chae Yee Soo, Moon Joon Ho, Kang Byung Woog, Park Jun Seok, Park Jin Young, Choi Gyu Seog

Abstract excerpt

Hypoxia-inducible factor-1 (HIF-1) is the key regulator of cellular response to hypoxia and presumably plays a central role in the control of tumor growth. The present study analyzed polymorphisms of HIF-1α gene and their impact on the prognosis for patients with colorectal cancer. Four hundred and forty-five consecutive patients with surgically resected colorectal adenocarcinoma were enrolled in the present...

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PMID: 20635169
DOI: 10.1007/s12032-010-9618-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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