Article
An investigation of relationships between hypoxia-inducible factor-1 alpha gene polymorphisms and ovarian, cervical and endometrial cancers.
Cancer detection and prevention - 1 Jan 2007
Konac Ece, Onen H Ilke, Metindir Jale, Alp Ebru, Biri Aydan Asyali, Ekmekci Abdullah
Abstract excerpt
BACKGROUND: DNA sequence variations in HIF-1 alpha gene might yield changes both in the production outcomes and in the activities of the gene. Overexpression of the HIF-1 alpha subunit, resulting from intratumoral hypoxia and genetic alterations, has been demonstrated in common human cancers and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
