Article
Evidence of association between GDF5 polymorphisms and congenital dislocation of the hip in a Caucasian population.
Osteoarthritis and cartilage - 1 Sept 2010
Rouault K, Scotet V, Autret S, Gaucher F, Dubrana F, Tanguy D, El Rassi C Yaacoub, Fenoll B, Férec C
Abstract excerpt
OBJECTIVE: Congenital dislocation of the hip (CDH) is a multifactorial disease which involves genetic factors that are still unidentified. Recently, a functional polymorphism (rs143383) of the 5'-untranslated region of GDF5 (Growth/Differentiation Factor 5) - previously reported to be associated with osteoarthritis - has been associated with CDH in a Chinese population. The aim of our study was to determine...
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