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DNA hypermethylation of GDF5 in developmental dysplasia of the hip (DDH)

23 Jul 2019

Abstract excerpt

INTRODUCTION & OBJECTIVE: Developmental Dysplasia of the Hip (DDH) is one of the most common congenital skeletal anomalies. Body of evidence suggests that genetic variations in GDF5 are associated with susceptibility to DDH. DDH is a multifactorial disease and its etiology has not been entirely determined. Epigenetic changes such as DNA methylation could be linked to DDH. In this scheme, we hypothesized that...

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PMID: 31338995
DOI: 10.1002/mgg3.887

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