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Article

Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study.

Arthritis research & therapy - 1 Jan 2008

Dai Jin, Shi Dongquan, Zhu Pengsheng, Qin Jianghui, Ni Haijian, Xu Yong, Yao Chen, Zhu Lunqing, Zhu Hongtao, Zhao Baocheng, Wei Jia, Liu Baorui, Ikegawa Shiro, Jiang Qing, Ding Yitao

Abstract excerpt

INTRODUCTION: Congenital dysplasia of the hip is an abnormal seating of the femoral head in the acetabulum, mainly caused by shallow acetabulum and lax joint capsule. Genetic factors play a considerable role in the pathogenesis of congenital dysplasia of the hip. The gene growth differentiate factor 5 (GDF5) has been implicated in skeletal development and joint morphogenesis in humans and mice. A functional...

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Source

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Identifiers

PMID: 18947434
DOI: 10.1186/ar2540
PMCID: PMC2592816

Genes

GDF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study.PMID 18947434Read ↗

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