Is GDF5 gene promoter polymorphism +104T/C associated with osteoarthritis in the Eastern of Turkey population?

doi:10.14715/cmb/2017.63.8.14

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Is GDF5 gene promoter polymorphism +104T/C associated with osteoarthritis in the Eastern of Turkey population?

Cellular and molecular biology (Noisy-le-Grand, France) - 30 Aug 2017

Tülüce Y, Yildirim I H, Özkol H, Edi Z L, Delen V

Abstract excerpt

Osteoarthritis (OA) is the most common form of arthritis. Genetic factors have been shown to play important roles in the etiology of OA. The gene growth differentiation factor 5 (GDF5) has been implicated in skeletal development and joint morphogenesis in human and mice. A functional single nucleotide polymorphism (SNP) +104T/C in the 5'-UTR of GDF5 (rs143383) was reported to be associated with osteoarthritis...

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PMID: 28886316
DOI: 10.14715/cmb/2017.63.8.14

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GDF5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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