Article
Interleukin 1 beta (IL1B) gene polymorphisms are not associated with gastric carcinogenesis in Germany.
Anticancer research - 1 Feb 2010
Wex Thomas, Leodolter Andreas, Bornschein Jan, Kuester Doerthe, Kähne Thilo, Kropf Siegfried, Albrecht Caroline, Naumann Michael, Roessner Albert, Malfertheiner Peter
Abstract excerpt
BACKGROUND: Polymorphisms of interleukin-1 beta gene (IL1B-511C>T) are considered as risk factor for gastric carcinogenesis, but conflicting data have been reported recently. PATIENTS AND METHODS: The distribution of the four major IL1B variants (IL1B-3737C>T, -1464G>C, - 511C>T, -31T>C) were analyzed in 116 and 142 patients with gastric cancer and 'high risk gastritis', respectively, as well as 94 healthy...
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