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Article

Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells).

The Journal of neuroscience : the official journal of the Society for Neuroscience - 14 Jul 2010

Nagamoto-Combs Kumi, Combs Colin K

Abstract excerpt

The transcription factor family, nuclear factor of activated T cells (NFAT), regulates immune cell phenotype. Four different calcium/calmodulin-regulated isoforms have been identified in the periphery, but isoform expression in microglia, the resident immune cells of the CNS, has not been fully defined. In this study microglial NFAT isoform expression and involvement in regulating inflammatory responses in murine...

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Identifiers

PMID: 20631193
DOI: 10.1523/JNEUROSCI.0828-10.2010
PMCID: PMC2914496

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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