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Article

Genetic analysis of three important genes in pigmentation and melanoma susceptibility: CDKN2A, MC1R and HERC2/OCA2.

Experimental dermatology - 1 Sept 2010

Ibarrola-Villava Maider, Fernandez Lara P, Pita Guillermo, Bravo Jerónimo, Floristan Uxua, Sendagorta Elena, Feito Marta, Avilés José A, Martin-Gonzalez Manuel, Lázaro Pablo, Benítez Javier, Ribas Gloria

Abstract excerpt

The CDKN2A gene is regarded as the major familial malignant melanoma (MM) susceptibility gene. Human pigmentation is one of the main modulators of individual risk of developing MM. Therefore, the genes involved in the determination of skin colour and tanning response are potentially implicated in MM predisposition and may be useful predictors of MM risk in the general population. The human melanocortin-1 receptor...

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Identifiers

PMID: 20629734
DOI: 10.1111/j.1600-0625.2010.01115.x

Genes

OCA2
HERC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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