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Article

Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma.

The Journal of investigative dermatology - 1 Feb 2010

Duffy David L, Zhao Zhen Z, Sturm Richard A, Hayward Nicholas K, Martin Nicholas G, Montgomery Grant W

Abstract excerpt

We have previously described the role of red hair (melanocortin-1 receptor, MC1R) and blue eye (oculocutaneous albinism type II, OCA2) gene polymorphisms in modulating the risk of cutaneous malignant melanoma (CMM) in a highly sun-exposed population of European descent. A number of recent studies, including genome-wide association studies, have identified numerous polymorphisms controlling human hair, eye, and...

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Source

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Identifiers

PMID: 19710684
DOI: 10.1038/jid.2009.258
PMCID: PMC3672059

Genes

OCA2
ASIP
TYR
TYRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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