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Article

Factors affecting reproducibility between genome-scale siRNA-based screens.

Journal of biomolecular screening - 1 Aug 2010

Barrows Nicholas J, Le Sommer Caroline, Garcia-Blanco Mariano A, Pearson James L

Abstract excerpt

RNA interference-based screening is a powerful new genomic technology that addresses gene function en masse. To evaluate factors influencing hit list composition and reproducibility, the authors performed 2 identically designed small interfering RNA (siRNA)-based, whole-genome screens for host factors supporting yellow fever virus infection. These screens represent 2 separate experiments completed 5 months apart...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20625183
DOI: 10.1177/1087057110374994
PMCID: PMC3149892

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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