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Article

Microsatellite mutation models: insights from a comparison of humans and chimpanzees.

Genetics - 1 Sept 2004

Sainudiin Raazesh, Durrett Richard T, Aquadro Charles F, Nielsen Rasmus

Abstract excerpt

Using genomic data from homologous microsatellite loci of pure AC repeats in humans and chimpanzees, several models of microsatellite evolution are tested and compared using likelihood-ratio tests and the Akaike information criterion. A proportional-rate, linear-biased, one-phase model emerges as the best model. A focal length toward which the mutational and/or substitutional process is linearly biased is a...

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Identifiers

PMID: 15454551
DOI: 10.1534/genetics.103.022665
PMCID: PMC1448085

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