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Article

SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies

12 Jul 2010

Abstract excerpt

BACKGROUND: The transcription factor SOX11 plays an important role in embryonic development of the central nervous system (CNS) and is expressed in the adult immature neuron but is normally not expressed in any other adult tissue. It has recently been reported to be implicated in various malignant neoplasms, including several lymphoproliferative diseases, by its specific expression and in some cases correlation...

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PMID: 20624318
DOI: 10.1186/1476-4598-9-187

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