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Article

Regulation of SOX11 expression through CCND1 and STAT3 in mantle cell lymphoma

10 Dec 2018

Abstract excerpt

Abstract The neural transcription factor SOX11 is usually highly expressed in typical mantle cell lymphoma (MCL), but it is absent in the more indolent form of MCL. Despite being an important diagnostic marker for this hard-to-treat malignancy, the mechanisms of aberrant SOX11 expression are largely unknown. Herein, we describe 2 modes of SOX11 regulation by the cell-cycle regulator cyclin D1 (CCND1) and the...

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Identifiers

PMID: 30530749
DOI: 10.1182/blood-2018-05-851667

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