Isolation and characterization of Streptomyces griseolus deletion mutants affected in cytochrome P-450-mediated herbicide metabolism.

doi:10.1007/BF00259676

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Article

Isolation and characterization of Streptomyces griseolus deletion mutants affected in cytochrome P-450-mediated herbicide metabolism.

Molecular & general genetics : MGG - 1 Jun 1991

Harder P A, O'Keefe D P, Romesser J A, Leto K J, Omer C A

Abstract excerpt

Metabolism of sulfonylurea herbicides by Streptomyces griseolus ATCC 11796 is carried out via two cytochromes P-450, P-450SU1 and P-450SU2. Mutants of S. griseolus, selected by their reduced ability to metabolize a fluorescent sulfonylurea, do not synthesize cytochrome P-450SU1 when grown in the...

Topics

Blotting, Southern
Chromatography, High Pressure Liquid
Chromosome Deletion
Cytochrome P-450 Enzyme System
Ferredoxins
Herbicides
Kinetics
Mutation
Streptomyces
Sulfonylurea Compounds

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