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Article

Characterization of mutations contributing to sulfathiazole resistance in Escherichia coli.

Antimicrobial agents and chemotherapy - 1 Jan 1998

Vedantam G, Guay G G, Austria N E, Doktor S Z, Nichols B P

Abstract excerpt

A sulfathiazole-resistant dihydropteroate synthase (DHPS) present in two different laboratory strains of Escherichia coli repeatedly selected for sulfathiazole resistance was mapped to folP by P1 transduction. The folP mutation in each of the strains was shown to be identical by nucleotide sequence analysis. A single C-->T transition resulted in a Pro-->Ser substitution at amino acid position 64. Replacement of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 9449266
DOI: 10.1128/AAC.42.1.88
PMCID: PMC105461

Genes

DHPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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