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Article

Proteasomal and autophagic degradative activities in spinal and bulbar muscular atrophy.

Neurobiology of disease - 1 Nov 2010

Rusmini Paola, Bolzoni Elena, Crippa Valeria, Onesto Elisa, Sau Daniela, Galbiati Mariarita, Piccolella Margherita, Poletti Angelo

Abstract excerpt

Spinal and bulbar muscular atrophy (SBMA or Kennedy's disease) is a fatal neurodegenerative disease characterized by the selective loss of motor neurons in the bulbar region of the brain and in the anterior horns of the spinal cord. The disease has been associated to an expansion of a CAG triplet repeat present in the first coding exon of the androgen receptor (AR) gene. SBMA was the first identified member of a...

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PMID: 20621188
DOI: 10.1016/j.nbd.2010.06.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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