Article
Functional variants of COX-2 and risk of tobacco-related oral squamous cell carcinoma in high-risk Asian Indians.
Oral oncology - 1 Aug 2010
Mittal Manasi, Kapoor Vaishali, Mohanti Bidhu Kalyan, Das Satya Narayan
Abstract excerpt
We assessed the association of COX-2 polymorphisms at promoter sites -1195, -765 and at 3'UTR (8473) in 193 patients with oral squamous cell carcinoma (OSCC) and 137 normal subjects by PCR-RFLP. Although no significant difference was observed in the frequency of COX-2 -1195G>A, -765G>C and 8473C>T single nucleotide polymorphisms (SNPs) between patients and controls, COX-2 -1195G/A genotype showed higher while...
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