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Article

Increased invasive, chemotactic and locomotive abilities of c-Ha-ras-transformed human breast epithelial cells.

Invasion & metastasis - 1 Jan 1991

Ochieng J, Basolo F, Albini A, Melchiori A, Watanabe H, Elliott J, Raz A, Parodi S, Russo J

Abstract excerpt

Transfection of the immortalized human breast epithelial cells MCF-10A with the mutated ras oncogene resulted in cell transformation (MCF-10A-neoT). Since the transformed state is usually associated with enhanced migratory activity, increased capability to invade basement membranes and to grow in...

Topics

Adenocarcinoma
Animals
Breast Neoplasms
Cell Division
Cell Movement
Cell Transformation, Neoplastic
Chemotaxis
Epithelium
Female
Genes, ras
Humans
Neoplasm Invasiveness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Proto-Oncogene Mas

Rats

Transfection

Source

Identifiers

PMID: 2061003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2061003-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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