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Article

5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.

British journal of cancer - 27 Jul 2010

Bracht K, Nicholls A M, Liu Y, Bodmer W F

Abstract excerpt

BACKGROUND: Colorectal cancer is (CRC) one of the commonest cancers and its therapy is still based on few drugs. Currently, no biological criteria are used to choose the most effective of the established drugs for treatment. METHODS: A panel of 77 CRC cell lines was tested for sensitivity to 5-fluorouracil (5FU) using the SRB assay. The responses were grouped into three categories and correlated with genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20606684
DOI: 10.1038/sj.bjc.6605780
PMCID: PMC2920028

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DCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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