Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single variants can explain the association between coronary heart disease and haplotypes in the apolipoprotein(a) locus.

Atherosclerosis - 1 Sept 2010

Shiffman Dov, Louie Judy Z, Rowland Charles M, Malloy Mary J, Kane John P, Devlin James J

Abstract excerpt

OBJECTIVE: LPA encodes apolipoprotein(a), and a CCTC haplotype in the LPA locus is associated with CHD. The 4399Met variant (rs3798220) of LPA has a risk estimate for CHD similar to that of the CCTC haplotype. We asked whether co-incidence with the 4399Met variant explained the association of the haplotype with CHD. METHODS: We stratified by the 4399Met variant and another LPA SNP (rs10455872) associated with CHD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apoprotein(a)
Share to California
Share to Case-Control Studies
Share to Coronary Disease
Share to Haplotypes
Share to Logistic Models
Share to Odds Ratio
Share to Risk Assessment

Source

Identifiers

PMID: 20605575
DOI: 10.1016/j.atherosclerosis.2010.05.009

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single variants can explain the association between coronary heart disease and haplotypes in the apolipoprotein(a) locus.PMID 20605575Read ↗

The Lipoprotein(a) rs3798220 and rs10455872 polymorphisms and coronary heart disease: a meta-analysis of 55,647 participants.Semantic proximity Read ↗

[Advances in the Association between Apolipoprotein (a) Gene Polymorphisms and Coronary Heart Disease].Semantic proximity Read ↗

Study of the association of 17 lipid-related gene polymorphisms with coronary heart disease.Semantic proximity Read ↗

The use of meta-analysis risk estimates for candidate genes in combination to predict coronary heart disease risk.Semantic proximity Read ↗

Common genetic variation in the ATP-binding cassette transporter A1, plasma lipids, and risk of coronary heart disease.Semantic proximity Read ↗

Cholesteryl ester transfer protein gene haplotypes, plasma high-density lipoprotein levels and the risk of coronary heart disease.Semantic proximity Read ↗

Genotypes and haplotypes predisposing to myocardial infarction: a multilocus case-control study.Semantic proximity Read ↗

Association of CETP Gene Polymorphisms and Haplotypes with Cardiovascular Risk.Semantic proximity Read ↗

Mutation in ABCA1 predicted risk of ischemic heart disease in the Copenhagen City Heart Study Population.Semantic proximity Read ↗

Two rare variants explain association with acute myocardial infarction in an extended genomic region including the apolipoprotein(A) gene.Semantic proximity Read ↗

Multiple less common genetic variants explain the association of the cholesteryl ester transfer protein gene with coronary artery disease.Semantic proximity Read ↗

Positive Association between APOA5 rs662799 Polymorphism and Coronary Heart Disease: A Case-Control Study and Meta-Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.