Article
Comparison of MHC class I risk haplotypes in Thai and Caucasian psoriatics shows locus heterogeneity at PSORS1.
Tissue antigens - 1 Nov 2010
Stuart P E, Nair R P, Hiremagalore R, Kullavanijaya P, Kullavanijaya P, Tejasvi T, Lim H W, Voorhees J J, Elder J T
Abstract excerpt
Earlier studies have shown that psoriasis in Japan and Thailand is associated with two different major histocompatibility complex (MHC) haplotypes - those bearing HLA-Cw6 and those bearing HLA-Cw1 and HLA-B46. In an independent case-control sample from Thailand, we confirmed the association of psoriasis with both haplotypes. No association was seen in Thai HLA-Cw1 haplotypes lacking HLA-B46, nor was HLA-Cw1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.